For me reading through the Hostile rpg is like returning home after a long absence. Why because of the fact that there's so much more to the game then simply another gritty Alien rpg knock off. Because for me Hostile is about exploration, expansion, and more in the face of adversity the likes of which mankind hasn't faced since the age of Exploration. The frontier aspect of the vast blackness of space within Hostile holds lots of potential. There isn't anyone coming to help you within the vastness of space.
Hostile is a 'lived in' universe that I know & understand this goes a long ways to helping me run a game set within this universe. So over the last couple of years that Hostile and 2d6 Cepheus Engine rpg's have been within my life there's been some excellent experiences at the table top level. Player's PC's are the blue collar guys & there's a tendency for players to get attached to said PC's even though they might not be alive for far too long.
Mixing & matching various 2d6 Cepheus Engine rpg resources with Hostile has both been very rewarding. Yet in some instances frustrating for players not used to the modular nature of 2d6 games. The easy of these rpg supplements simply being moved into play with some backstory has been interesting to watch as each DM molds Hostile into the game they want and need.